ThinkPad T16 AMD Ryzen ACPI issue, no keyboard no touchpad

I have been trying to get Qubes installed on a ThinkPad T16 Gen 1 with AMD CPU for a while. The latest try with Qubes 4.2.0-rc4 was relatively successful, however ACPI needs to be disabled and the onboard keyboard and touchpad do not work. This seems similar to the issues reported at My adventures with Qubes 4.1.1 on a Lenovo T14 Gen 3 - #21 by Scumbag

hcl-report output:

Qubes release 4.2.0-rc4

Brand:     LENOVO
Model:     21CHCTO1WW
BIOS:      R23ET70W (1.40 )

Xen:       4.17.2
Kernel:    6.4.8-1

RAM:       31508 Mb

  AMD Ryzen 7 PRO 6850U with Radeon Graphics
  Advanced Micro Devices, Inc. [AMD] Family 17h-19h PCIe Root Complex [1022:14b5] (rev 01)
  Advanced Micro Devices, Inc. [AMD/ATI] Rembrandt [Radeon 680M] [1002:1681] (rev d1) (prog-if 00 [VGA controller])

  Realtek Semiconductor Co., Ltd. RTL8111/8168/8411 PCI Express Gigabit Ethernet Controller [10ec:8168] (rev 0e)
  Qualcomm Technologies, Inc QCNFA765 Wireless Network Adapter [17cb:1103] (rev 01)

HVM:       Active
I/O MMU:   Active
TPM:       Device not found
Remapping: yes
Certified: no

To install, I booted the installer with kernel parameter acpi=off. The installer gives an error about not being able to create the boot entry, but this can be fixed manually with a live CD as mentioned on UEFI troubleshooting | Qubes OS

For booting, the kernel parameter acpi=noirq is required. Without this parameter the laptop reboots immediately after loading the kernel image. To boot to a graphical login screen, it is also required to add the nomodeset kernel parameter.

Probably due to the acpi kernel option, poweroff does not work, neither does the keyboard or touchpad. Current and older versions of Debian and Fedora work fine on this laptop.

I have to idea how to debug the ACPI issue further. Any tips on how to do that would be greatly appreciated.