Q4.1 install from scratch (official iso file) fails

I have already tested 4.1rc2, and everything looks good (haven’t try use debian 10 as default template, and downloading template with whonix as describe here).

Are you trying to rerun initial setup or this happen in first time boot?
What configuration you use in installation {keyboard layout, custom storage}?
Have you check journalctl ? journalctl -u qubesd.service