Yes. Here is my super-short introduction to Qubes explaining which VMs are preinstalled. They are based on Fedora by default.
Qubes OS is hardened by the fact that you run everything in VMs, which are isolated from each other by hardware virtualization.
You can have several VMs, some of which are based on Debian and some on Fedora.
Yes.
Qubes is Xen, and it runs minimized Fedora in a special, privileged VM (dom0, adminVM), which is only used to manage other VMs.
On Qubes, you have all these in VMs.
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Indeed, looks abandoned.