FWIW, I experimented with installing Qubes on an slightly different Inspiron model (also had a Ryzen processor - one of the older APU models) only to kinda give up with some minor successes noted (I captured still shots & maybe even shot a short video showing it installed & usable before rebooting). That exact same laptop now has a different Linux on it with a periodic issue that still makes it a kinda hard to appreciate even now (but I will one day try Qubes on it again). I learned that booting anything but the Windows (switched out the hard drive to preserve the windows separately) would sometimes lead to a hang at start even without Qubes.
Here’s the thing that I know - I have a fully installed & testable Linux on there at the moment. If I boot up & press ESC key repeatedly near approximately the time frame where the CLI screen is displaying the initramfs statement (possible that this is less related than it appears to me, maybe I badly correlated those points of time), the cursor will either switch from large format to small format (switching of graphics modes?) & I can relent & let it continue or it will remain at the large format for the cursor & never really seems to ever continue (like something is trying to execute that is unworkable & ESC is allowing me to blindly skip but I’ve also had it boot up without intereference [every reboot is a fresh chance not to start up but once you have it up it is fine] & see that it goes right on up sometimes all on it’s own).
I’ve gotten Qubes on there in the past with difficulty proceeding due to this seeming random issue which I may have initially thought was Qubes related (absorbed a lot of my time trying on multiple occassions). At the moment, I like the installed Linux & it’s hardly worth fighting. I never published the HCL because of the continuing issue that made it unclear what was going on. My guess about the ESC may not be useful or relevant but it does seem to help with me booting consistently with the existing Linux (no BIOS options seem to alter this behavior - legacy or UEFI).
Today, I can boot it up & update it & use it by following that general formula. The Qubes install just needs to accomplish all the things that Qubes installation needs while realizing that the reboots will lead to fighting with it some more & the shutdowns/starts are also likely to lead to fighting with it some more - that is until someone can come up with a solution to why this was necessary.
I mentioned this only since for anyone insisting upon attempting installs on any proprietary BIOS/proprietary hardware system (mostly I’m pointing a finger at all commercial laptops), your mileage may greatly vary. Also, it may one day work out in the end.