So during a troubleshoot of kernel and crashes I ran a 2nd Qubes innstalation to a USB disk.
After some testing I wanted to boot back to my main Qubes just to discover the boot entry was gone.
Did some searches and found that this should resolve it for me:
efibootmgr -v -c -L Qubes -l /EFI/qubes/xen.efi -d /dev/nvme0n1p1 (yup correct disk).
That indeed gives me the entry, but if I choose it Im thrown right in to bios.
Maybe the entry isnt correct for a 4.1 innstalation?