I am having this issue, on the latest 4.1, with all dom0 packages up to date and running kernel 6.0.7
Haven’t confirmed by moving clock to another VM though. Confused as it seems to be solved below.
Also and possibly related, it takes a long time (several minutes) for the trackpad to work after resume, and there’s qubes-suspend.service timeout messages in journalctl logs
Also experiencing this: All qubes frozen after resuming from suspend on Librem 14 · Issue #8061 · QubesOS/qubes-issues · GitHub
Downgrading kernel in appVMs works (but not sysvms otherwise WiFi doesn’t work)