Thank you. I was able to install Qubes Windows Tools (Accepting current security risks QSB-091) Which fixed the issue.
For others wanting to install QWT on Qubes OS 4.2 I took the following steps:
I entered the following in dom0:
sudo qubes-dom0-update qubes-windows-tools-4.1.69
Then I entered the install command in dom0:
qvm-start <VMname> --install-windows-tools
And following the rest of the QWT installation guide for 4.1