Qubesd fails to start ANY qube

● qubesd.service - Qubes OS daemon
     Loaded: loaded (/usr/lib/systemd/system/qubesd.service; enabled; preset: enabled)
     Active: active (running) since Sat 2025-12-27 18:00:25 CET; 57min ago
   Main PID: 4233 (qubesd)
     Status: "qubesd online and operational"
      Tasks: 2 (limit: 4354)
     Memory: 44.1M
        CPU: 23.050s
     CGroup: /system.slice/qubesd.service
             └─4233 /usr/bin/python3 /usr/bin/qubesd

Dez 28 18:57:27 dom0 qubesd[4233]:   File "/usr/lib/python3.11/site-packages/qubes/api/admin.py", line 1628, in vm_stats
Dez 28 18:57:27 dom0 qubesd[4233]:     info_time, info = self._send_stats_single(info_time, info,
Dez 28 18:57:27 dom0 qubesd[4233]:                       ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
Dez 28 18:57:27 dom0 qubesd[4233]:   File "/usr/lib/python3.11/site-packages/qubes/api/admin.py", line 1574, in _send_stats_single
Dez 28 18:57:27 dom0 qubesd[4233]:     (info_time, info) = self.app.host.get_vm_stats(info_time, info,
Dez 28 18:57:27 dom0 qubesd[4233]:                         ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
Dez 28 18:57:27 dom0 qubesd[4233]:   File "/usr/lib/python3.11/site-packages/qubes/app.py", line 398, in get_vm_stats
Dez 28 18:57:27 dom0 qubesd[4233]:     info = self.app.vmm.xc.domain_getinfo(0, 1024)
Dez 28 18:57:27 dom0 qubesd[4233]:            ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^
Dez 28 18:57:27 dom0 qubesd[4233]: xen.lowlevel.xc.Error: (13, 'Permission denied')

After my upgrade to 4.3 did not worked, I used a snapshot to revert back. No no qube can start, it’s unrelated to the template. It tells me I would not have enough memory to start the desired domain, but that can’t be true.
Does anyone gets smart out of the error message?

Did a reinstall of some qube packages.

Now:

[MainProcess libvirtaio._update_handle:393] virEventAsyncIOImpl: update_handle(watch=0, event=3)

I guess just some files are missing?

QubesDaemonCommunicationError: Failed to connect to qubesd service: [Errno 2] Datei oder Verzeichnis nicht gefunden
at line 543
of file /usr/lib/python3.11/site-packages/qubesmanager/utils.py.

Now there are “just” permission errors.