I’ve used this laptop as my primary machine for 2 to 3 weeks. It performs very well with Qubes 4.1. The system has never crashed going into or waking up from suspend. However sys-net has to be restarted after waking up from suspend nearly every time. This is a minor inconvenience and is the only glitch I’ve found so far. I’ve confirmed the following works:
On a 1 to 10 scale of usability (10 being best) I would rate the machine a 9 with Qubes 4.1.