I’ve been having a number of issues with my Librem 14 and Qubes.
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xfce4-power-manager sometimes does not recognize plugging/unplugging the power adapter.
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The battery sometimes decides to not charge. Even with the power adapter plugged in, the battery level will stay at 63%, for example.
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The headphones do not work yet, but evidently there is a firmware update in the near future to fix this.
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xfce4-power-manager sometimes does not recognize the lid is closed and does not suspend. I’ve been having to manually suspend before closing the lid.
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After rebooting today, I currently cannot login to Qubes due to some sort of login loop. The OS boots to the login prompt after successfully decrypting the luks drive. Upon entering the incorrect password, the login fails with an appropriate error message. Upon entering the correct password, the login prompt just resets.
I think some more tweaks are required before calling this compatible out of the box.