There are interesting questions about Qubes from a Hacker News discussion.
The part about the qubes dom0 being ‘outdated’ is worrying, because one of the important things to think about for good Xen linux-on-linux (PV) performance is to use a recent kernel on the dom0, and recent version of xen.
Even ultra conservative debian stable (buster, right now) uses something fairly up to date, and xen 4.11. I’d be concerned about using anything older than that.
I of course know about the FAQ, but this seems not to be covered by it.
And if you are paranoid enough to need Qubes, then you want ECC memory to defend against side channel attacks.
Do these complains make sense?