Hi,
Does somebody has the NUC Box from Novacustom already and is using it with QubesOS? I would like to switch to it but need a very stable system for working with my clients.
Currently using a T480 with 64GB as my daily machine with Qubes on it, but the CPU performance is not enough.
Appreciate any information about it. 
I don’t know about Novacustom NUCs, but the System76 meer8 is the one that I own and works perfectly.
Although I love its portability, I must tell you that this things overheat a lot under heavy load. Beware of that, because if you run heavy workloads, you’ll likely reach a thermal throttle.