Iptables not available in sys-net in Qubes OS 4.2.1

Qubes OS is using random MAC address for WiFi and persistent MAC address for Ethernet connections by default.
If you want to use persistent MAC address for WiFi then change “Cloned MAC Address” in WiFi connection settings to Preserve or Permanent.

I don’t know what could change iif == "eth0" to iif 2.
You can also use iifgroup 1 instead of iif == "eth0".