Install Qube OS On USB External Hard Drive

Hello Everyone !!!
Can I install Qube on External Hard Drive And Enable
Sys-usb!? Any suggestions !? Or Should i install it on the Internal hardDrive !?

Thanks in advance

Yes, but you won’t be able to attach the USB hub with the external device
with Qubes OS to sys-usb.

Any suggestions !? Or Should i install it on the Internal hardDrive !?

Moreover internal should be a lot faster.

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