A bit more background:
Obviously I was trying to install to an NVMe drive. I also dont dont actually know why I cared (or should care) about using UEFI without CSM
I followed all the UEFI troubleshooting in the Official Qubes documentation
I followed all the guidance in Fom’s giant list of Qubes OS workarounds
I tried creating the installation media on different USB sticks, using different settings, using different software, I tried buying a new and extremely overpriced USB 2 stick (seriously why do these things cost so much more than USB 3 sticks…) following all the above steps each time.
Yes, the definition of insanity is trying the same thing over and over again expecting different results. Yes, I might be little bit insane.
It wasn’t until I was finally successful installing on a SATA drive without CSM that I got a bit suspicous. I noticed I could boot when I installed to a SATA drive in AHCI mode instead of AMD-RAID mode.
Buried deep without the settings of my x399 mobo i found that NVMe was in RAID mode.
Disabled NVMe RAID and installed perfectly without following any of the aforementioned troubleshooting steps.
Now I haven’t actually tried to fix any of the power saving settings like suspend/hibernate, so I can’t attest to those working on x399, although that might have more with using nvidia GPUs
Now its time to figure out PCI Passthrough for nvidia