Just found this update for 4.2, my openVPN connection has not been working since upgrading to 4.2. I tried the new qubes-vpn-handler.sh by @etaz, but getting the same results as I did with old version:
2024-02-10 18:17:45 OpenVPN 2.6.8 x86_64-redhat-linux-gnu [SSL (OpenSSL)] [LZO] [LZ4] [EPOLL] [PKCS11] [MH/PKTINFO] [AEAD] [DCO]
2024-02-10 18:17:45 library versions: OpenSSL 3.0.9 30 May 2023, LZO 2.10
2024-02-10 18:17:45 DCO version: N/A
2024-02-10 18:17:45 NOTE: the current --script-security setting may allow this configuration to call user-defined scripts
2024-02-10 18:17:45 TCP/UDP: Preserving recently used remote address: [AF_INET]999.999.999.99:443
2024-02-10 18:17:45 Socket Buffers: R=[131072->131072] S=[16384->16384]
2024-02-10 18:17:45 Attempting to establish TCP connection with [AF_INET]999.999.999.99:443
2024-02-10 18:17:45 TCP connection established with [AF_INET]999.999.999.99:443
2024-02-10 18:17:45 TCPv4_CLIENT link local: (not bound)
2024-02-10 18:17:45 TCPv4_CLIENT link remote: [AF_INET]999.999.999.99:443
2024-02-10 18:18:45 TLS Error: TLS key negotiation failed to occur within 60 seconds (check your network connectivity)
2024-02-10 18:18:45 TLS Error: TLS handshake failed
2024-02-10 18:18:45 Fatal TLS error (check_tls_errors_co), restarting
2024-02-10 18:18:45 SIGUSR1[soft,tls-error] received, process restarting
2024-02-10 18:18:45 Restart pause, 1 second(s)