The issue seems to be hardware-related, particularly with modern motherboards that have multiple PCI devices. When setting up Qubes OS for the first time with the default configuration, the sys-usb qube attempts to connect to all these PCI devices, which can cause the system to freeze permanently. This can be a significant barrier for new users who may not be motivated to troubleshoot the problem. They need to know that they should disable the automatic creation of sys-usb and manually create it later, selecting only the specific PCI devices responsible for USB functionality that do not cause system freezes. How can this process be made clearer for new users?
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