can i installl and run security research toools
There is no reason you can’t run security research tools. The one limitation you may encounter are layer-2 protocol (ethernet) tricks either won’t work, or if can be made to work will be tricky.
If you are attempting to run suspected malware in a controlled environment you may want to dedicate a separate physical box with another dedicated physical machine acting as a firewall and tunnel gateway.
x86_64 (either Intel or AMD variants) CPUs are so untrustworthy that any machine malware is tested on is a “sacrificed” machine.
Yes, something like Kali Linux or ParrotOS is fine.