Hello again. Since nobody replied on my request I decided to do it (configuration) myself. Everything was going ok until I tried to start minicom. If by order, then first I changed that value from modem to ttyUSB0 and saved these settings as DFL (save confirming message was present). Then exited minicom. But when I start minicom with sudo minicom it returns an error saying that there is no such file or directory as dev/ttyUSB0. I repeated operation with modem connection turned on but this changed nothing. I have two guesses about this:
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Maybe it’s Qubes peculiarity causing this issue since there is no dev directory in its VM file system. But if these settings are set in modem itself, not in qube, then this is not the reason.
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It needs simcard to be inserted in modem when all operation is being performed and these settings are being saved in simcard (I did all this without simcard in modem). But it looks more like non-sense since it’s modem mode switching not the simcard, so why it should be somehow involved? Of course I could just check it out by repeating all with simcard inserted but now I would like use other simcard that never was there and never seen any mac address (I would like use set-up without mac address involved, so that’s why I’m trying to switch this USB stick to the modem mode). Escpecially because I’m 99% sure that simcard is not the reason of all of this in any way.
So, generally, if this is Qubes specific issue then I need help. He does all this with Huawei stick so in theory it should work with my stick too since the same manufacturer. 
If I’m just doing something wrong then - still need help. 