The GRUB configuration on my Framework 13, 13th Gen, Intel is NOT at this location on Qubes 4.1.2. I have tested this extensively.
The location is boot/efi/EFI/qubes/grub.cfg
, in case anyone finds this and the above does not work.
My guide for a Framework 13, 13th Gen Intel laptop on Qubes 4.1.2: Framework Laptop 13th Gen, Intel i5-1340P.