Jul 16 10:51:40 dom0 kernel: nvme nvme0: I/O 550 QID 1 timeout, completion polled
Jul 16 10:51:30 dom0 libvirtd[2181]: internal error: connection closed due to keepalive timeout
Jul 16 10:51:10 dom0 kernel: nvme nvme0: I/O 549 QID 1 timeout, completion polled
Maybe it’s an issue with your storage.
Try to switch the storage mode from RAID to AHCI/NVME or disable Intel Volume Management Device (VMD) in BIOS.
UPD:
Or not, it seems like an issue with the lack of resources in sys-usb: