Two SSDs One Laptop :) Help with "un-dual booting" Pls

Want to run Qubes 4.1.2 on laptop that has 2 nvme ssds installed, so that qubes runs off of one ssd and windows off of another.

Question: since this is kind of a non-dual boot since they are separate physical drives, what is the most secure way to install and boot each system ?

Trying to see if there is a benefit to being able use two physical SSDs instead of two partitions.

Please let me know your thoughts, thanks.

anyone? pls:)