No, in fact use of the GPU (not even talking about NPUs here) in QubesOS is a bit of a sticking point. With a single GPU, you currently cannot have hardware acceleration in qubes, you need a second one you can passthrough (there are some experimental ways around that, but they are not fully developed and are not trivial).
From what I have read in the forums, QubesOS 4.3 will not change significantly the GPU situation (I’ll be happy to be told otherwise :-)).
What is really important for QubesOS is to have lots of RAM and a good (fast and reliable) SSD.