IMO Qubes is unstable, every new version of Qubes, template updates, simmilar things broken my setup. For example i wrote some scripts using iptables, but after update 4.2 they were broken. In first version 4.2 also didn’t work autostart scripts.
Members above says: “just backup it, and you will have no problems with it”. But i know cases where backups were broken How to solve the problem of missing backup-header [urgent].
I’m using arch with syncthing for data replicaltion on mobile device. In case if laptop will die, i can restore my file from mobile device.