Possible indicator of compromise

Hello everyone,

I am writing to ask you a question.

Following a security incident I have resumed using QubesOS.

I secured the USB with the command:
sudo qubesctl state.sls qvm.usb-keyboard

Everything is fine but I am prompted at every boot to create the qube for the USB again.

Could this be a bug or could this be a possible indicator of compromise?

Thanks in advance.

What is the exact wording? Did you connect all your USB controllers to the sys-usb?