Nvidia driver problems

I think you should open the issue on Qubes OS github:

Then ask about this issue on the Xen developers matrix channel or mailing list and provide the link to the opened issue there:

The Fedora 41 will be released on 22 Oct and after this it should be used as a dom0 OS in Qubes OS 4.3 shortly.
Then you can get the Qubes OS 4.3 testing build from here for a test:
Index of /qubes/iso-testing/
Qubes OS 4.2 Signed Weekly Builds

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