This thread is a feedback for everyone with a thinkpad T480s with QubesOS 4.0 that want to try QubesOS 4.1 alpha
What is better in 4.1 than in 4.0 :
QubesOS is overall more reactive, more fast
You can now disable and enable the mic from the FN keys from the keyboard, wich was not possible before
You can disable and enable the sound from the FN keys from the keyboard, wich was not possible before
At the time that I installed QubesOS 4.1 alpha several weeks ago, the problem for the T480s i encountered and the solution :
Don't use debian 10 template for sys-net and sys-firewall because the wifi and ethernet interface are not working, use fedora instead
At the time that I installed QubesOS alpha several weeks ago, the problem which are not specific to T480s I encountered and the solution :
For the sys-usb with debian 10 template, the yubikey is not recognised and so you also need to switch to the fedora template
default-mngt-dvm will not work with debian-10 [because of this issue](https://forum.qubes-os.org/t/qubes-updater-jinja-py-no-such-file-or-directory/4311/3), change the template to fedora 33.
Conclusion : Everything in QubesOS 4.1 is working perfectly fine to use it as a daily driver on a thinkpad T480s and is working better than on Qubesos 4.0, enjoy ! Just use fedora 33 as default template instead of debian 10.
I will update my post about T480s when more update for QubesOS will come