I have the P14s AMD Gen2 currently here. Qubes R4.1 Beta installs out of the box. It works and seems usable, but Wifi (Realtek 8852AE) and resume from suspend dont work.
Resume at least lets appear the unlock screen before screen freezes/turns black and writes some logs (amdgpu, gfx ring stuff, maybe grafics?), but had no time to dig deeper.
Brightness Control (FN) works with Kernel 5.10.60 (current-testing).
Kernel 5.13.* (= Fepitres kernel-latest builds) reboot (loop) immediately before anything appears on screen.
I will try to get amdgpu and wifi drivers running, maybe that solves resume problems too.