Internal ssd + external ssd security

I have an internal ssd with windows and an external ssd with qubes os.
if i boot qubes os , can a virus from the internal windows disk compromise my qubes os while booting ?

Hi @parmenides, welcome to the Community! It seems your questions is similar to the one answered below:

In other words, it’s not as secure as using Qubes bare-metal. But it’s still much more secure than using anything else.