That depends on your workflow. See this topic for a list of community-recommended computers:
I have the Purism Librem 14v1-01, which is unique in that it has hardware kill switches for the Wi-Fi/Bluetooth modem and camera/microphone above the keyboard. Here is my latest HCL report about it:
For various reasons, I want to transition to either the upcoming Librem 16 or a MSI PRO Z790-P II motherboard with Dasharo firmware, so I have a similar situation as you do. However, I will mention that I am inclined to get the motherboard due to it simply being available right now.