This is not very useful. The exact wording of the error would help us to help you.
Open the Settings
of this qube, tab Advanced
and look what is chosen as Virtualization mode. If this is PVH
then you are probably safe, since this kind of virtualization is very strong. You should use HVM
if you attach any devices to this qube. PV
is not recommended and less secure. More details: Standalones and HVMs | Qubes OS.
This looks like those file are not persistent: Templates | Qubes OS. This should help: How to make any file persistent (bind-dirs) | Qubes OS.