I chained together qubes to make this work. I’m not sure its the best approach.
Example:
sys-mullvad: Set your firewall settings to only allow connections from the Mullvad IPs. Set your vpn to auto start when qube loads. I used this guide to do that: Using Mullvad VPN in Qubes
sys-whonix: Standard tor connection.
sys-mullvad-whonix: Uses sys-mullvad for the network.
What it looks like in practice.
sys-mullvad start and connects to the VPN.
Then sys-mullvad-whonix starts and connects to Mullvad thru sys-mullvad. Then connects to tor.
(You can go a step further and chain another VPN too: Example: sys-mullvad-tor-proton.)
Slow, but when needed, it could save your life as the world spirals further into dystopia.
You could also replace Lokinet for the Tor part of the chain. That will be my next test.