I would not treat it as equivalent to a separate airgapped machine. A non-networked qube removes a lot of everyday network exposure, but it still shares the same physical hardware, Xen/dom0, firmware, and user workflows with the rest of the system.
For notes or moderately sensitive files, that may be a reasonable tradeoff. For a crypto seed, I would prefer a hardware wallet or another offline storage method where the seed never has to be typed into a general-purpose computer. If you do use an offline qube, I’d at least make the threat model explicit and be very strict about clipboard/file transfer paths.