"But why trust Fedora?"

[renehoj]

I don’t think they are going to make dom0 OS independent, but if dom0 becomes less overloaded, than the OS shouldn’t matter.

Reproducible Builds Fedora vs Debian

There’s almost zero chance of the project moving to Debian for dom0 imo. Other options have been put forward, as you should know from GitHub. Once we have a fully working sys-gui,which can be Debian based, then dom0 starts to fade away. I never presume to speak for the Qubes team. When I comment in the Forum or in the mailing lists I speak for myself.