This one seems to be totally compatible, provided you get the very latest beta version of the OS. It won’t work with the now-current release. Once I did that I have had zero hardware issues. (Index of /qubes/iso/)
Be advised it has no audio jack, so you’ll need an HDMI splitter (or USB (ugh) speakers).
I’m going to have to add an addendum to this. I don’t have an audio jack, so I am using an HDMI splitter.
Every time I reboot the system I have to unplug one of my dual HDMI monitors to get sound to work (and then after plugging it back in I have to tell the system not to mirror the displays). Does anyone know of a simple command-line fix for the audio?
The audio issue turns out not to have anything with Qubes. Basically, you must run the splitter on the feed to your left-hand monitor.
If you don’t do that, xfce is somewhat forgiving: Unplug and replug the left monitor, and the sound comes back (and you get to re-set-up your displays). KDE is less forgiving; unplugging gives you the sound back, but plugging the left monitor back in makes it go away again.